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Table 2 Hematopoietic Neoplasms Accompanied by Eosinophilia

From: ICON: Eosinophil Disorders

Neoplasms in which eosinophils are likely to be clonal cells

   Acute eosinophilic leukemia

   CEL

   Acute myeloid leukemia with inv(16) (FAB AML M4eo)

   Chronic myeloid leukemia

   Myeloid neoplasms with PDGFR abnormalities (WHO types)

   Hematopoietic neoplasms with FGFR1 abnormalities (WHO types)

   Smoldering systemic mastocytosis

   Aggressive systemic mastocytosis

   Mast cell leukemia

Neoplasms in which eosinophils may or may not be part of the malignant clone

   Other MPN with eosinophilia*

   MDS with eosinophilia

   Other MDS/MPN overlap syndromes with eosinophilia*

   Indolent systemic mastocytosis

Neoplasms in which eosinophils usually are not part of the malignant clone

   Hodgkin disease

   B-or T-cell non-Hodgkin lymphoma

   Acute lymphoblastic leukemia

   Chronic lymphocytic leukemia

   Langerhans cell histiocytosis

  1. *Other MPN or MPN/MDS: neoplasms where no abnormalities in the PDGFR or FGFR1 genes are detectable.
  2. CEL, chronic eosinophilic leukemia; PDGFR, platelet-derived growth factor receptor; FGFR, fibroblast growth factor receptor; MPN, myeloproliferative neoplasm (s); MDS, myelodysplastic syndrome(s).
  3. WHO, World Health Organization.
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World Allergy Organization Journal

ISSN: 1939-4551

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