Table 1 Conditions associated with Hypereosinophilia (HE)

Reactive conditions

   Helminth infections

   Allergic reactions

   Atopic diseases

   Drug reactions (allergic or toxic)

   Scabies, other infestations

   Allergic bronchopulmonary aspergillosis

   Autoimmune diseases

   Other chronic inflammatory diseases

   Chronic graft-vs-host disease

   Lymphocytic/lymphoid variant HES

Neoplastic conditions involving the hematopoietic system (see Table 2)

   Myeloid neoplasms

   Mast cell neoplasms

   Lymphoid neoplasms

   Paraneoplastic conditions

   Solid tumors/malignancy

   Lymphoproliferative neoplasms

Idiopathic forms

   Idiopathic eosinophilia

   HE of uncertain (undetermined) significance

   Idiopathic HES

Rare syndromes associated with HE

   Gleich syndrome

   CSS

   EMS

   Omenn syndrome

   Hyper IgE syndrome

Hereditary HE (not otherwise specified)