From: WAO Guideline for the Management of Hereditary Angioedema
 | Route of administration | Efficacy | Safety | Limitation | Self-administration | Age, yrs | Cost |
---|---|---|---|---|---|---|---|
Berinert | IV | +++ | +++* | +†| + | All (≥12 in the United States) | High |
Cinryze | IV | +++ | +++* | +†| + | ≥12 | High |
Ruconest | IV | +++ | +++ | +‡ | - | ≥18 | High |
Icatibant | SC | +++ | +++ | +§ | + | ≥18 | High |
Ecallantide | SC | +++ | +++ | +|| | - | > 16 | High |