Table 1 Clinical Features and Source of Graft of Patients With Primary Immunodeficiency
From: Stem Cell Transplantation for Primary Immunodeficiency Disease: Experience of a Singapore Hospital
Patient | Sex | Diagnosis | Age at Presentation | Age at Diagnosis (mo) | Complications Before SCT |
|---|---|---|---|---|---|
1 | M | WAS | 3 d | 52 | CMV retinitis and colitis, infectious chronic diarrhea with rectal prolapse, hypoalbuminemia, iron deficiency anemia, failure to thrive |
2 | M | CGD | 4 mo | 12 | Intra-abdominal sepsis, right elbow subcutaneous abscess (Pseudomonas fluorescens), oral candidiasis, failure to thrive |
3 | M | X-linked SCID | 13 d | 4 | Systemic CMV disease (hepatitis, colitis, retinitis), chronic diarrhea, tinea, oral thrush |
4 | M | X-linked HIgM/CD40 ligand deficiency | 12 mo | 68 | Bronchiectasis and recurrent lung infections, Pneumocystis jiroveci pneumonitis, chronic diarrhea, pin worm infestations, chicken pox |
5 | M | LAD1 | 4 mo | 26 | Tracheostomy (laryngotracheoesophageal cleft type 2), bilateral aspiration pneumonia, left lower lobe abscess, skin ulcers, hiatus hernia with severe gastro-oesophageal reflux disease, gastrostomy site wound breakdown, hypertension, iron deficiency anemia, hypoalbuminemia, failure to thrive |
6 | M | X-linked HIgM/CD40 ligand deficiency | 3 mo | 22 | Pneumonia, recurrent upper respiratory tract infection, Salmonella septicemia and enteritis, gastroenteritis, failure to thrive |
7 | M | X-linked HIgM/CD40 ligand deficiency | 27 mo | 44 | Recurrent bronchitis, gastroenteritis, allergic rhinitis |