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Table 1 Influence of Mast Cell Numbers on Dexamethasone and Salbutamol Increase in Fibroblast Proliferation

From: Dexamethasone and Salbutamol Stimulate Human Lung Fibroblast Proliferation

 

Increase in Fibroblast Proliferation (%)

Mast Cell per Well

Dexamethasone

Salbutamol

15 × 103

349 ± 37*

348 ± 39*

25 × 103

352 ± 36*

405 ± 58*

35 × 103

387 ± 41*

566 ± 76*

  1. Fetal lung fibroblasts were preincubated with either dexamethasone (10-8 M) or salbutamol (10-7 M) and then incubated with different concentrations of mast cell sonicate. Fibroblast proliferation was evaluated and expressed as % increase over the value obtained with mast cell alone (as described in Materials and Methods). Data are the mean ± standard error of the mean of 5 experiments performed in triplicates.
  2. *P < 0.0001.
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World Allergy Organization Journal

ISSN: 1939-4551

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