Skip to main content
Figure 1 | World Allergy Organization Journal

Figure 1

From: Antihistaminic, Anti-Inflammatory, and Antiallergic Properties of the Nonsedating Second-Generation Antihistamine Desloratadine: a Review of the Evidence

Figure 1

The allergic cascade. Mast cell mediators, including cytokines, cause degranulation and contribute to the bidirectional messaging with other inflammatory cells or their precursors, lymphocyte activity, and migration of immune cells to inflammatory sites. CNS, central nervous system; ECP, eosinophil cationic protein; ICAM, intracellular adhesion molecule; Ig, immunoglobulin, IL, interleukin; LT, leukotriene; MBP, mannose-binding protein; MHC II, major histocompatability complex; PGs, prostaglandins. Reprinted with permission from Baena-Cagnani et al [4].

Back to article page

World Allergy Organization Journal

ISSN: 1939-4551

Contact us