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Figure 3 | World Allergy Organization Journal

Figure 3

From: Soluble Guanylyl Cyclase is Reduced in Airway Smooth Muscle Cells From a Murine Model of Allergic Asthma

Figure 3

cGMP production in ASMCs from CONTROL and OVA-sensitized rats. The ASMCs were incubated for 15 minutes in the presence of IBMX as described in the Materials and Methods. cGMP production was determined in the presence of Cch, SNP, and ODQ as described in the Materials and Methods. The cGMP produced was estimated in duplicate using a radioimmunoassay kit from Amersham. Each value is the mean ± of 5 different experiments. In both groups, the number of cell culture plates was obtained for a pool of 5 rats. The statistical significance between CONTROL versus OVA was established as P < 0.05 (*) and P < 0.001 (**).

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