Table 2 Genotype Distributions and Allele Frequencies of 4 BDNF Polymorphisms for Asthmatic Patients Versus Control Group (Figures in Parentheses Indicate Percentages)
From: Association of BDNF Gene Polymorphism With Asthma in Polish Children
Polymorphism | n | Asthma | n | Control | PValue | OR with 95%CI |
|---|---|---|---|---|---|---|
Rs12273363 | ||||||
Genotypes | ||||||
CC | 144 | 4 (2.78) | 216 | 5 (2.31) | 0.373 | 1.25 0.81-1.92 |
CT | 30 (20.83) | 59 (27.31) | ||||
TT | 110 (76.39) | 152 (70.37) | ||||
Alelles | ||||||
C | 288 | 38 (13.20) | 432 | 69 (15.98) | 0.336 | |
T | 250 (86.80) | 363 (84.02) | ||||
Rs6265 | ||||||
Genotypes | ||||||
AA | 146 | 3 (2.05) | 218 | 9 (4.13) | 0.224 | |
AG | 37 (25.34) | 68 (31.19) | 1.42 0.95-2.12 | |||
GG | 106 (72.60) | 141 (64.68) | ||||
Alelles | ||||||
A | 292 | 43 (14.73) | 436 | 86 (19.72) | 0.092 | |
G | 249 (85.27) | 350 (80.28) | ||||
Rs2030324 | ||||||
Genotypes | ||||||
TT | 146 | 31 (21.23) | 214 | 53 (24.77) | 0.061 | 1.35 1.00-1.82 |
CT | 62 (42.47) | 108 (50.47) | ||||
CC | 53 (36.30) | 53 (24.77) | ||||
Alelles | ||||||
T | 292 | 124 (42.50) | 428 | 214 (50.00) | 0.048* | |
C | 168 (57.50) | 214 (50.00) | ||||
Rs7124442 | ||||||
Genotypes | ||||||
CC | 131 | 79 (60.31) | 227 | 126 (55.51) | 0.354 | 0.93 0.68-1.32 |
CT | 41 (31.30) | 87 (38.33) | ||||
TT | 11 (8.40) | 14 (6.17) | ||||
Alelles | ||||||
C | 262 | 199 (75.96) | 454 | 339 (74.67) | 0.720 | |
T | 63 (24.04) | 115 (25.33) |