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Table 1 SOTI Protocol for Grape Allergy

From: Wine Allergy in a Wine-Growing District: Tolerance Induction in a Patient With Allergy to Grape Lipid-Transfer Protein

Parameter

SOTI procedure

Starting dose of grape

10 mL of 20 g of grapes diluted 1:1024 with 0.9% sodium chloride, corresponding to 19.5 mg of grapes

Time between steps

30 minutes

Increment of steps

Doubling doses

Number of steps

14

Time for whole procedure

3 days

Maximal dose

20 g of grapes