Figure 1From: Pathogenic Mechanisms of Idiopathic Nonallergic RhinitisTRP thermometer and aromatherapy. The various TRP ion channels respond to different temperatures, chemicals, osmolarity, and other physical stimuli. The chemicals include many spices. The channels may respond to a large number of other chemical structures. Heterotetramers of these TRP proteins may vastly increase the variety of stimuli that can lead to trigeminal nerve depolarization.Back to article page