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Table 5 Change in Lung Function, eNO, and BHR Between 2 Visits According to Mattress Exposure to Dust Mite Allergen*

From: Long-Term Effects of Allergen Sensitization and Exposure in Adult Asthma: A Prospective Study

Der p 1 (Mattress)

 

FEV1 (L)

FEV1 (% Predicted)

FVC (L)

FVC (% Predicted)

eNO (ppb)

PD20 (Doubling Doses)

Between Group Doubling Dose Difference PD20 (95% CI)

Not exposed

N

84

84

67

67

58

48

1.26

 

Mean

-0.03

1.77

0.01

1.73

-2.89†

0.82†‡

(0.44 to 2.08)

 

(95% CI)

(-0.12 to 0.05)

(-1.14 to 4.69)

(-0.13 to 0.15)

(-2.49 to 5.95)

(1.16-1.59)

(0.27-1.36)

 

Exposed

N

80

79

70

70

61

38

t test, P = 0.003

 

Mean

0.01

2.57

0.04

2.91

-3.60†

-0.44

ANOVA, P = 0.001

 

(95% CI)

(-0.06 to 0.08)

(-0.17 to 5.31)

(-0.09 to 0.17)

(-1.00 to 6.82)

(1.14-1.85)

(-1.07 to 0.19)

 
  1. *Lung function and BHR: mean changes (95% CI). eNO: geometric mean (95% CI for ratio).
  2. †P < 0.05 vs baseline; ‡P < 0.05 vs exposed.