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Table 5 Change in Lung Function, eNO, and BHR Between 2 Visits According to Mattress Exposure to Dust Mite Allergen*

From: Long-Term Effects of Allergen Sensitization and Exposure in Adult Asthma: A Prospective Study

Der p 1 (Mattress)   FEV1 (L) FEV1 (% Predicted) FVC (L) FVC (% Predicted) eNO (ppb) PD20 (Doubling Doses) Between Group Doubling Dose Difference PD20 (95% CI)
Not exposed N 84 84 67 67 58 48 1.26
  Mean -0.03 1.77 0.01 1.73 -2.89† 0.82†‡ (0.44 to 2.08)
  (95% CI) (-0.12 to 0.05) (-1.14 to 4.69) (-0.13 to 0.15) (-2.49 to 5.95) (1.16-1.59) (0.27-1.36)  
Exposed N 80 79 70 70 61 38 t test, P = 0.003
  Mean 0.01 2.57 0.04 2.91 -3.60† -0.44 ANOVA, P = 0.001
  (95% CI) (-0.06 to 0.08) (-0.17 to 5.31) (-0.09 to 0.17) (-1.00 to 6.82) (1.14-1.85) (-1.07 to 0.19)  
  1. *Lung function and BHR: mean changes (95% CI). eNO: geometric mean (95% CI for ratio).
  2. P < 0.05 vs baseline; ‡P < 0.05 vs exposed.