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Table 3 Change in Spirometry, eNO, and BHR Between 2 Visits in the Whole Population and for Atopic and Nonatopic Subjects Only*

From: Long-Term Effects of Allergen Sensitization and Exposure in Adult Asthma: A Prospective Study

  

FEV1 (L)

FEV1 (% Predicted)

FVC (L)

FVC (% Predicted)

eNO (ppb)

PD20 (Doubling Doses)

All subjects

N

163

162

137

137

118

85

 

Mean

-0.00

2.27†

0.02

2.33

-3.25†

0.29

 

(95% CI)

(-0.06 to 0.06)

(0.29-4.26)

(-0.07 to 0.12)

(-0.50 to 5.17)

(1.22-1.62)

(-0.13 to 0.72)

Atopic

N

134

133

110

110

97

72

 

Mean

-0.00

2.72†

0.04

3.30†

-3.93†

0.39

Nonatopic

(95% CI)

(-0.06 to 0.05)

(0.54-4.90)

(-0.06 to 0.14)

(0.18-6.42)

(1.25-1.73)

(-0.04 to 0.83)

 

N

29

29

27

27

21

13

 

Mean

-0.00

0.21

-0.06

-1.61

-1.10

-0.27

 

(95% CI)

(-0.18 to 0.17)

(-4.83 to 5.24)

(-0.32 to 0.21)

(-8.57 to 5.35)

(0.86-1.61)

(-1.84 to 1.30)

  1. *Lung function and BHR: mean changes (95% CI). eNO: geometric mean (95% CI for ratio).
  2. †P < 0.05 vs baseline.