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Table 3 Change in Spirometry, eNO, and BHR Between 2 Visits in the Whole Population and for Atopic and Nonatopic Subjects Only*

From: Long-Term Effects of Allergen Sensitization and Exposure in Adult Asthma: A Prospective Study

   FEV1 (L) FEV1 (% Predicted) FVC (L) FVC (% Predicted) eNO (ppb) PD20 (Doubling Doses)
All subjects N 163 162 137 137 118 85
  Mean -0.00 2.27† 0.02 2.33 -3.25† 0.29
  (95% CI) (-0.06 to 0.06) (0.29-4.26) (-0.07 to 0.12) (-0.50 to 5.17) (1.22-1.62) (-0.13 to 0.72)
Atopic N 134 133 110 110 97 72
  Mean -0.00 2.72† 0.04 3.30† -3.93† 0.39
Nonatopic (95% CI) (-0.06 to 0.05) (0.54-4.90) (-0.06 to 0.14) (0.18-6.42) (1.25-1.73) (-0.04 to 0.83)
  N 29 29 27 27 21 13
  Mean -0.00 0.21 -0.06 -1.61 -1.10 -0.27
  (95% CI) (-0.18 to 0.17) (-4.83 to 5.24) (-0.32 to 0.21) (-8.57 to 5.35) (0.86-1.61) (-1.84 to 1.30)
  1. *Lung function and BHR: mean changes (95% CI). eNO: geometric mean (95% CI for ratio).
  2. P < 0.05 vs baseline.