Table 1 Demographic and Clinical Features of Patients With Low and High Risks for NSAID Hypersensitivity
From: A Novel Phenotype of Nonsteroidal Anti-Inflammatory Drug Hypersensitivity The High-Risk Patient
Low-Risk Group | High-Risk Group | P | |
|---|---|---|---|
n | 179 | 124 | -- |
Age ± SD (range), y | 30.6 ± 12.8 (9-69) | 32.7 ± 14.5 (10-90) | 0.18 |
Sex, n (%) | |||
Female | 120 (67.0) | 93 (75.0) | -- |
Male | 59 (32.9) | 31.0 (25.0) | 0.1 |
Atopic disease, n (%) | |||
Any atopic disease | 162 (90.5) | 104 (83.8) | -- |
Rhinitis | 117 (65.3) | 76 (61.2) | -- |
Rhinitis and asthma | 41 (22.9) | 26 (20.9) | -- |
Asthma | 2 (1.1) | 1 (0.8) | -- |
Rhinitis, asthma, and dermatitis | 2 (1.1) | 0 (0) | -- |
Rhinitis and dermatitis | 0 (0) | 1 (0.8) | -- |
None | 17 (9.4) | 20 (16.1) | 0.1 |
Pharmacological pattern, n (%) | |||
Cross reactor | 146 (81.5) | 92 (74.1) | -- |
Single reactor | 33 (18.4) | 32 (25.8) | 0.1 |
Clinical pattern, n (%) | |||
Cutaneous | 99 (55.3) | 61 (49.1) | 0.3 |
Mixed | 79 (44.1) | 62 (50.0) | 0.3 |
Systemic | 1 (0.5) | 1 (0.8) | 0.6 |
Immediate-type skin tests, +/n (%) | 148/173 (85.5) | 97/105 (92.3) | 0.1 |