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Table 1 Demographic and Clinical Features of Patients With Low and High Risks for NSAID Hypersensitivity

From: A Novel Phenotype of Nonsteroidal Anti-Inflammatory Drug Hypersensitivity The High-Risk Patient

  Low-Risk Group High-Risk Group P
n 179 124 --
Age ± SD (range), y 30.6 ± 12.8 (9-69) 32.7 ± 14.5 (10-90) 0.18
Sex, n (%)    
   Female 120 (67.0) 93 (75.0) --
   Male 59 (32.9) 31.0 (25.0) 0.1
Atopic disease, n (%)    
   Any atopic disease 162 (90.5) 104 (83.8) --
   Rhinitis 117 (65.3) 76 (61.2) --
   Rhinitis and asthma 41 (22.9) 26 (20.9) --
   Asthma 2 (1.1) 1 (0.8) --
   Rhinitis, asthma, and dermatitis 2 (1.1) 0 (0) --
   Rhinitis and dermatitis 0 (0) 1 (0.8) --
   None 17 (9.4) 20 (16.1) 0.1
Pharmacological pattern, n (%)    
   Cross reactor 146 (81.5) 92 (74.1) --
   Single reactor 33 (18.4) 32 (25.8) 0.1
Clinical pattern, n (%)    
   Cutaneous 99 (55.3) 61 (49.1) 0.3
   Mixed 79 (44.1) 62 (50.0) 0.3
   Systemic 1 (0.5) 1 (0.8) 0.6
   Immediate-type skin tests, +/n (%) 148/173 (85.5) 97/105 (92.3) 0.1