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Figure 4 | World Allergy Organization Journal

Figure 4

From: Anti-Immunoglobulin E Therapy

Figure 4

Omalizumab mechanisms of action. Omalizumab/anti-IgE decreases free IgE, IgE bound to FcεRI, and FcεRI expression on mast cells, basophils, dendritic cells, and monocytes. It also reduces tissue infiltration by T and B lymphocytes, eosinophils, mast cells, and basophils.

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