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Table 2 Median/Mean Values of Spirometry, Blood Eosinophil Count, TSIgE and Serum Cytokines, Prevaccination and Postvaccination on Both Groups on First and Second Phases

From: Clinical Efficacy and Laboratory Improvement of Bacillus Calmette-Guerin Vaccination on Adult Atopic Asthma A Cohort Study

     Postvaccination   
Dependent Variables Prevaccination 4 Wk 8 Wk 12 Wk 6 Mo 9 Mo
Thrice BCG Group       
   PEFR (L/min) 360.5 ± 61.1 403.5 ± 71.9*,† 409.5 ± 63.9*,† 428.0 ± 77.6*,† 398.3 ± 101.0*,‡ 380 ± 86.1§,‡
   FEV1 (L) 2.02 ± 7.6    2.33 ± 0.7*,†   
   MMEV (L/s) 2.52 ± 1.3    3.12 ± 1.3*,†   
   Eosinophil count (/μL) 608 ± 493.1    516 ± 522.1§,‡ 453.9 ± 313.1§,‡ 410 ± 299.0*,‡
   TSIgE (IU/mL) 1366 ± 1934.6    1395 ± 1563.7§,‡ 1502.82 ± 2184.0§,‡ 1440 ± 2084.4§,‡
   IFN-γ (pg/mL) 3.55 ± 2.2    4.22 ± 3.8§,‡ 4.58 ± 2.8*,† 4.67 ± 0.5*,‡
   IL-4 (pg/mL) 0.04 ± 0.039    0.08 ± 0.05*,‡ 0.09 ± 0.03*,† 0.1 ± 0.04*,†
   TGF-β1 (pg/mL) 54,396 ± 6908    50,720 ± 7111.4*,‡ 38,066 ± 9279||,‡ 48,271 ± 9634||,‡
Placebo Group      Single BCG Group
   PEFR (L/min) 360 ± 53.3 343 ± 67.4§,† 325 ± 63.8*,† 315.50 ± 72.9*,† 371 ± 73.98§,‡ 346 ± 95.8§,‡
   FEV1 (L) 2.04 ± 0.65    1.64 ± 0.5*,†   
   MMEV (L/s) 2.51 ± 1.2    2.01 ± 1.95*,†   
   Eosinophil count (/μL) 649 ± 580.7    393 ± 358.4*,‡ 569 ± 553.7§,‡ 593 ± 582§,‡
   Total IgE (IU/mL) 887 ± 794.4    1053 ± 863.2§,‡ 927 ± 1076.3§,‡ 791 ± 1094.3§,‡
   IFN-γ (pg/mL) 3.65 ± 1.8    3.85 ± 1.95§,‡ 5.25 ± 0.90*,† 4.81 ± 1.30*,‡
   IL-4 (pg/mL) 0.08 ± 0.13    0.08 ± 0.11§,‡ 0.16 ± 0.09*,† 0.16 ± 0.13*,†
   TGF-β1 (pg/mL) 53,910 ± 7525    51,480 ± 6084.9§,‡ 40,853 ± 12,772||,‡ 45,942 ± 9453||,‡
  1. Values are expressed as mean or median ± SD; *P < 0.05; ||P < 0.001; §P > 0.05.
  2. Bold line separates the first and second phases; †P < 0.05 between groups; ‡P > 0.05 between groups.
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World Allergy Organization Journal

ISSN: 1939-4551

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