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  1. Review

    Tiotropium in asthma: what is the evidence and how does it fit in?

    Despite current therapeutic approaches asthma remains uncontrolled in a significant proportion of patients. Short-acting anticholinergic bronchodilators have a very long history of use in asthma, and recent da...

    David M. G. Halpin

    World Allergy Organization Journal 2016 9:29

    Published on: 14 September 2016

  2. Original research

    Exposure to positively- and negatively-charged plasma cluster ions impairs IgE-binding capacity of indoor cat and fungal allergens

    Environmental control to reduce the amount of allergens in a living place is thought to be important to avoid sensitization to airborne allergens. However, efficacy of environmental control on inactivation of ...

    Kazuo Nishikawa, Takashi Fujimura, Yasuhiro Ota, Takuya Abe, Kareem Gamal ElRamlawy, Miyako Nakano, Tomoaki Takado, Akira Uenishi, Hidechika Kawazoe, Yoshinori Sekoguchi, Akihiko Tanaka, Kazuhisa Ono and Seiji Kawamoto

    World Allergy Organization Journal 2016 9:27

    Published on: 6 September 2016

  3. Review

    Prevention of food and airway allergy: consensus of the Italian Society of Preventive and Social Paediatrics, the Italian Society of Paediatric Allergy and Immunology, and Italian Society of Pediatrics

    Allergic sensitization in children and allergic diseases arising therefrom are increasing for decades.

    Giuseppe di Mauro, Roberto Bernardini, Salvatore Barberi, Annalisa Capuano, Antonio Correra, Gian Luigi de’ Angelis, Iride Dello Iacono, Maurizio de Martino, Daniele Ghiglioni, Dora Di Mauro, Marcello Giovannini, Massimo Landi, Gian Luigi Marseglia, Alberto Martelli, Vito Leonardo Miniello, Diego Peroni…

    World Allergy Organization Journal 2016 9:28

    Published on: 18 August 2016

  4. Review

    The use of inhaled corticosteroids in pediatric asthma: update

    Despite the availability of several formulations of inhaled corticosteroids (ICS) and delivery devices for treatment of childhood asthma and despite the development of evidence-based guidelines, childhood asth...

    Elham Hossny, Nelson Rosario, Bee Wah Lee, Meenu Singh, Dalia El-Ghoneimy, Jian Yi SOH and Peter Le Souef

    World Allergy Organization Journal 2016 9:26

    Published on: 12 August 2016

  5. Review

    Dissemination of definitions and concepts of allergic and hypersensitivity conditions

    Allergy and hypersensitivity can affect people of any age and manifest with problems in a range of organ systems. Moreover, they can have a significant impact on the quality of life of patients and their famil...

    Luciana Kase Tanno, Moises A. Calderon, Helen E. Smith, Mario Sanchez-Borges, Aziz Sheikh and Pascal Demoly

    World Allergy Organization Journal 2016 9:24

    Published on: 9 August 2016

  6. Original research

    Assessing worldwide research activity on probiotics in pediatrics using Scopus database: 1994–2014

    A wide variety of probiotic products has been introduced into the market in the past decade. Research trends and activity on probiotics help understand how these products were evolved and their potential futur...

    Waleed M. Sweileh, Naser Y. Shraim, Samah W. Al-Jabi, Ansam F. Sawalha, Belal Rahhal, Rasha A. Khayyat and Sa’ed H. Zyoud

    World Allergy Organization Journal 2016 9:25

    Published on: 25 July 2016

  7. Review

    Eosinophilic esophagitis: published evidences for disease subtypes, indications for patient subpopulations, and how to translate patient observations to murine experimental models

    Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of the esophagus and commonly classified as a Th2-type allergy. Major advances in our understanding of the EoE pathophysiology have recently be...

    Anne C. A. Mudde, Willem S. Lexmond, Richard S. Blumberg, Samuel Nurko and Edda Fiebiger

    World Allergy Organization Journal 2016 9:23

    Published on: 15 July 2016

  8. Case report

    Successful use of cyclosporine as treatment for eosinophilic cystitis: a case report

    Eosinophilic cystitis is a rare inflammatory disorder characterized by eosinophilic infiltration of all layers of the urinary bladder wall. Due to lack of consensus and potential for side effect from various t...

    Sohaib Aleem, Bharat Kumar, Mary Beth Fasano, Elizabeth Takacs and Antoine Emile Azar

    World Allergy Organization Journal 2016 9:22

    Published on: 8 July 2016

  9. Review

    Eosinophilic bioactivities in severe asthma

    Asthma is clearly related to airway or blood eosinophilia, and asthmatics with significant eosinophilia are at higher risk for more severe disease. Eosinophils actively contribute to innate and adaptive immune...

    Tara F. Carr, Sergejs Berdnikovs, Hans-Uwe Simon, Bruce S. Bochner and Lanny J. Rosenwasser

    World Allergy Organization Journal 2016 9:21

    Published on: 27 June 2016

  10. Review

    Particularities of allergy in the Tropics

    Allergic diseases are distributed worldwide and their risk factors and triggers vary according to geographical and socioeconomic conditions. Allergies are frequent in the Tropics but aspects of their prevalenc...

    Luis Caraballo, Josefina Zakzuk, Bee Wah Lee, Nathalie Acevedo, Jian Yi Soh, Mario Sánchez-Borges, Elham Hossny, Elizabeth García, Nelson Rosario, Ignacio Ansotegui, Leonardo Puerta, Jorge Sánchez and Victoria Cardona

    World Allergy Organization Journal 2016 9:20

    Published on: 27 June 2016

  11. Position article and guidelines

    World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Vitamin D

    The prevalence of allergic diseases is approximately 10 % in infants whose parents and siblings do not have allergic diseases and 2030 % in those with an allergic first-degree relative. Vitamin D is involved in ...

    Juan José Yepes-Nuñez, Alessandro Fiocchi, Ruby Pawankar, Carlos A. Cuello-Garcia, Yuan Zhang, Gian Paolo Morgano, Kangmo Ahn, Suleiman Al-Hammadi, Arnav Agarwal, Shreyas Gandhi, Kirsten Beyer, Wesley Burks, Giorgio W. Canonica, Motohiro Ebisawa, Rose Kamenwa, Bee Wah Lee…

    World Allergy Organization Journal 2016 9:17

    Published on: 17 May 2016

  12. Original research

    Insights, attitudes, and perceptions about asthma and its treatment: a multinational survey of patients from Europe and Canada

    Asthma surveys completed within the past 10 years in the Americas and the Asia-Pacific region have shown significant underassessment of asthma severity in addition to undertreatment of asthma and have suggeste...

    Joaquin Sastre, Leonardo M. Fabbri, David Price, Hans Ulrich Wahn, Jean Bousquet, James E. Fish, Kevin Murphy and Malcolm R. Sears

    World Allergy Organization Journal 2016 9:13

    Published on: 4 May 2016

  13. Meeting abstracts

    XXIV World Allergy Congress 2015

    A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts

    Heung-Man Lee, Il-Ho Park, Jae-Min Shin, Hyun-Sun Yoon, Gyeong Yul Park, Margit Zeher, Katsuhiko Matsui, Saki Tamai, Reiko Ikeda, Drsushil Suri, Dranu Suri, Marzieh Heidarzadeh Arani, Azwin Lubis, Anang Endaryanto, Shinichiro Koga, Lee Ju Suk…

    World Allergy Organization Journal 2016 9(Suppl 1):14

    Published on: 19 April 2016

    This article is part of a Supplement: Volume 9 Supplement 1

  14. Debate

    Debates in allergy medicine: specific immunotherapy efficiency in children with atopic dermatitis

    Allergen specific immunotherapy (AIT) has been the only pathogenetically relevant treatment of IgE-mediated allergic diseases (ADs) for many years. The use of AIT for atopic dermatitis (AD) treatment is dubiou...

    Tatiana A. Slavyanakaya, Vladislava V. Derkach and Revaz I. Sepiashvili

    World Allergy Organization Journal 2016 9:15

    Published on: 18 April 2016

    The Erratum to this article has been published in World Allergy Organization Journal 2016 9:38

  15. Original research

    Clinical characteristics of patients seeking medical advice for nasal symptoms in Bulgaria with special focus on children

    In an attempt to circumvent low response rates and high cost of classical epidemiological trials, we carried out a real-life survey among practicing physicians consulting patients for nasal symptoms. In this f...

    Tihomir B. Mustakov, Todor A. Popov, Tanya Z. Kralimarkova, Maria T. Staevska and Vasil D. Dimitrov

    World Allergy Organization Journal 2016 9:11

    Published on: 4 April 2016

  16. Original research

    International survey on skin patch test procedures, attitudes and interpretation

    Skin patch test is the gold standard method in diagnosing contact allergy. Although used for more than 100 years, the patch test procedure is performed with variability around the world. A number of factors ca...

    Luciana K. Tanno, Razvigor Darlenski, Silvia Sánchez-Garcia, Matteo Bonini, Andrea Vereda, Pavel Kolkhir, Dario Antolin-Amerigo, Vesselin Dimov, Claudia Gallego-Corella, Juan Carlos Aldave Becerra, Alexander Diaz, Virginia Bellido Linares, Leonor Villa, Lanny J. Rosenwasser, Mario Sanchez-Borges, Ignacio Ansotegui…

    World Allergy Organization Journal 2016 9:8

    Published on: 4 March 2016

  17. Position article and guidelines

    World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Prebiotics

    The prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10 % and reaches 20–30 % in those with an allergic first-degree relative. Intestinal microbiota ...

    Carlos A. Cuello-Garcia, Alessandro Fiocchi, Ruby Pawankar, Juan José Yepes-Nuñez, Gian Paolo Morgano, Yuan Zhang, Kangmo Ahn, Suleiman Al-Hammadi, Arnav Agarwal, Shreyas Gandhi, Kirsten Beyer, Wesley Burks, Giorgio W. Canonica, Motohiro Ebisawa, Rose Kamenwa, Bee Wah Lee…

    World Allergy Organization Journal 2016 9:10

    Published on: 1 March 2016

  18. Original research

    CD4+CD25highCD127- regulatory T-cells in COPD: smoke and drugs effect

    Chronic obstructive pulmonary disease (COPD) is a progressive lung disorder characterized by poorly reversible airway obstruction and its pathogenesis remains largely misunderstood. Local changes of regulatory...

    Alessandra Chiappori, Chiara Folli, Francesco Balbi, Emanuela Caci, Anna Maria Riccio, Laura De Ferrari, Giovanni Melioli, Fulvio Braido and Giorgio Walter Canonica

    World Allergy Organization Journal 2016 9:5

    Published on: 12 February 2016

  19. Review

    Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases

    Biomarkers of disease activity have come into wide use in the study of mechanisms of human disease and in clinical medicine to both diagnose and predict disease course; as well as to monitor response to therap...

    Dean D. Metcalfe, Ruby Pawankar, Steven J. Ackerman, Cem Akin, Frederic Clayton, Franco H. Falcone, Gerald J. Gleich, Anne-Marie Irani, Mats W. Johansson, Amy D. Klion, Kristin M. Leiferman, Francesca Levi-Schaffer, Gunnar Nilsson, Yoshimichi Okayama, Calman Prussin, John T. Schroeder…

    World Allergy Organization Journal 2016 9:7

    Published on: 11 February 2016

  20. Reviewer acknowledgement

    Reviewer acknowledgement 2015

    The editors of World Allergy Organization Journal would like to thank all of our reviewers who have contributed to the journal in Volume 8 (2015).

    Alessandro Fiocchi and Erika Jensen-Jarolim

    World Allergy Organization Journal 2016 9:6

    Published on: 8 February 2016

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