From: Is allergic sensitization relevant in severe asthma? Which allergens may be culprits?
Enfumosa study | Tenor study | SARP Study | |
---|---|---|---|
Study design/location | Cross-sectional European multicentre study (9 Countries) | U.S. Multicentre Observational study | Observational cross-sectional multicentre study (9 sites in U.S. and 1 site in U.K.) |
Patients (N.) with severe asthma | 163 | 2282 (48% OF TOTAL) | 204 |
Age characteristics | Age range: 17-65 yrs | Mean age ± SD : 38.9 ± 20.92 yrs | Mean age ± SD: 41 ± 13 yrs |
Sex | Sex ratio (F/M) : 4.4 / 1 | Not reportedc | Females: 64% |
≥1 Positive skin prick test | 58% (VS. 78% OF Controlled asthmatics) | - | 71% (VS. 85% of mild and 87% of moderate asthma) |
Mean total serum IgE | 109 KU/L-1, 95% CI: 85-139 | 106.6 IU/mla | 2.0 ± 7.6b |
References | 2 | 3 | 4 |