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Table 1 Clinical characteristics of mothers with acute allergic reactions to galacto-oligosaccharide (GOS) in mothers’ milk formula

From: An unusual cause of food-induced anaphylaxis in mothers

Subject ID

Pregnancy status

History of atopy

Volume of milk consumed (ml)

Amount of GOS consumed (g)

Time to onset of symptoms (min)

Symptoms

Adrenaline received

Skin prick test to GOS wheal size (mm)

P1

Prenatal

Chronic rhinitis

Unknown

Unknown

30

Rhinorrhea, Throat tightness and itch, difficulty breathing, hives, red skin

Yes, dose unknown

8

P2

Prenatal

Chronic rhinitis, childhood asthma, sea urchin allergy, bird’s nest allergy

200

1.5

15

Eye swelling, congested nose, itchy throat, cough, wheezing

No

6

P3

Prenatal

Aspirin allergy

250

1.9

30

Eye and lip swelling, congested nose, itchy throat, hives, red skin

500 μg

6

P4

Postnatal

Chronic rhinitis, allergy to prawns and crabs, Bactrim allergy

200–250

1.5–1.9

30

Eye swelling, congested nose, throat tightness, cough, red skin

No

6

P5

Prenatal

Chronic rhinitis

100

0.72 g

40

Angioedema, running nose, watery eyes, sneezing,itchy throat, throat tightness, cough, wheezing, hoarseness of voice

No

5

P6

Postnatal

Chronic rhinitis

240

1.8

30

Eye swelling, facial itch, congested/running nose

No

4

  1. Legend: GOS Galacto-oligosaccharide