Skip to main content

Table 3 Main current diagnostic procedures for allergy/hypersensitivity (adapted from [48])

From: Dissemination of definitions and concepts of allergic and hypersensitivity conditions

IgE-mediated hypersensitivity diagnostic procedures

T-Lymphocyte-mediated hypersensitivity diagnostic procedures

In vitro

 − Serum allergen specific-IgE

 − Serum (or plasma) tryptase

 − Basophil activation test (BAT)

 − Cellular Antigen Stimulation Test (CAST)- Enzyme linked ImmunoSorbent Assay (ELISA)

In vitro

 − Lymphocyte transformation blood test

 − Enzyme-Linked ImmunoSpot (ELISPOT)

 − CD69 expression

In vivo

 − Skin tests

  • Skin prick tests

  • Intradermal skin tests

 − Provocation test

In vivo

− Skin tests

  • Skin patch tests/Photopatch tests

  • Intradermal skin tests

− Provocation test