From: The care pathway for children with urticaria, angioedema, mastocytosis
Tools | Hereditary angioedema |
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First line | Clinical presentation: recurrent angioedema or abdominal pain in the absence of hives, without urticaria |
Family history | |
Laboratory: C4 and C1 inhibitor serum levels | |
Second line | Genetic analysis: mutations in C1-INH gene (Serping1 gene), mapped to chromosome 11 (11q12-q13.1) |