Table 1 Clinical manifestations of patients with MAS
From: Allergic manifestations and cutaneous histamine responses in patients with McCune Albright syndrome
Pt # | Age (Yr) | Sex | Tanner stage | Polyostotic fibrous dysplasia | Characteristic café-au- lait spots | Gonadotropin independent precocious puberty | Non autoimmune thyroid disease | # MAS features | Max flare (mm) | Max wheal (mm) | Manifestations of atopy/hypersensitivity |
|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 17 | M | 5 | Yes | Yes | Yes | Yes | 4 | 107 | 21 | anaphylaxis (latex), drug allergies (morphine, penicillin), asthma H. Pylori negative ulcer Other sensitivities (topical benzocaine) |
2 | 15 | F | 5 | No | Yes | Yes | No | 2 | 156 | 18 | anaphylaxis (strawberries), drug allergies (ibuprofen, tylenol), multiple food allergies, chronic gastritis |
3 | 12 | F | 3 | Yes | Yes | Yes | No | 3 | 105 | 11 | anaphylaxis (cashews), atopic dermatititis,drug allergy (erythromycin), Other sensitivities (nickel, surgical tape) |
4 | 13 | F | 3 | Yes | Yes | Yes | No | 3 | 98 | 7 | anaphylaxis (penicillin) |
5 | 13 | F | 3 | Yes | Yes | Yes | No | 3 | 100 | 17 | positive skin testing (ragweed, dust mites), asthma, atopic dermatitis, chronic urticaria |
6 | 10 | F | 1 | Yes | Yes | No | Yes | 3 | 70 | 12 | multiple drug allergies (methimazole, propylthiouracil) |
7 | 8 | F | 3 | Yes | Yes | Yes | No | 3 | 112 | 10 | drug allergy (letrozole) Other sensitivities (gluten, surgical tape), chronic urticaria |
8 | 17 | F | 5 | Yes | Yes | Yes | No | 3 | 98 | 14 | asthma, latex allergy |
9 | 7 | F | 2 | No | Yes | Yes | No | 2 | 75 | 18 | atopic dermatitis, seasonal rhinitis, chronic urticaria |
10 | 7 | F | 2 | No | Yes | Yes | No | 2 | 92 | 14 | asthma, seasonal rhinitis |
11 | 16 | M | 5 | Yes | Yes | No | No | 2 | 135 | 17 | none |