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Table 1 Recent Data About Desloratadine Use in Respiratory Diseases: Clinical Trials and End Points

From: Review of Desloratadine Data Using the ARIA Guidelines

Criteria

Data

End Point

SAR

Pradalier et al. Allergy. 2007;62:1331 (AERONEF)

TSS

 

Kosa L. JACI. 2008;121: S51 (open label)

Nasal, ocular

 

Keith et al. Clin Ther. 2007;121;1151-1155

Nasal, ocular, respiratory, and overall symptoms

 

Meltzer et al. Ann Allergy Asthma Immunol.

TSS, nasal airflow

 

2006;96;363-368.

 

PAR

Kim et al. Ann Allergy Asthma Immunol.

TSS; PNIF

 

2006;96:460 (TNSS, PNIF)

 

IAR/PER

ACCEPT

 

Asthma

Rossi et al. Allergy. 2005; 60:416.

TNSS, asthma symptoms in peds

Meta-analysis

Canonica et al. Allergy. 2007;62:359.

TSS, nasal airflow

Peds

Tassinari et al. AAAAI 2006. (SAR/PAR TSS)

SAR, PAR, TSS

 

Rossi et al. Allergy. 2005; 60:416-417

TNSS, asthma symptoms in peds

 

Dizdar et al. Int J Pediatr Otorhinoloaryngol. 2007;71:843-849

PRN use in peds