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Table 1 EAACI/GA(2)LEN/EDF/WOA Algorithm for Pharmacological Treatment of CIU[8]

From: Challenges in the Management of Chronic Urticaria

nsAH

   ↓ If symptoms persist after 2 weeks:

nsAH updosing (up to 4 times)

   ↓ If symptoms persist after 1-4 weeks:

Add leukotriene antagonist or change nsAH

Exacerbation: systemic steroids (for 3-7 days)

   ↓ If symptoms persist after 1-4 weeks:

Add cyclosporine A, H2 antihistamine,a dapsone, omalizumab

Exacerbation: systemic steroids (for 3-7 days)

  1. aIn the United States, adding H2-receptor antagonist to the H1 antihistamine comes as a second step in the CU management algorithm.