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Table 3 Adverse Events Observed in at Least 2 Subjects in a Randomized, Double-Blind, Placebo-Controlled Trial Evaluating Prophylactic Use of C1-Esterase Inhibitor Therapy Irrespective of Causality[46]

From: Hereditary Angioedema Caused By C1-Esterase Inhibitor Deficiency: A Literature-Based Analysis and Clinical Commentary on Prophylaxis Treatment Strategies

Adverse Event*

Number of Adverse Events

Number of Subjects (N = 24)

Sinusitis

8

5

Rash

7

5

Headache

4

4

Upper respiratory tract infection

3

3

Viral upper respiratory tract infection

5

3

Bronchitis

2

2

Limb injury

2

2

Back pain

2

2

Pain in extremity

2

2

Pruritus

2

2

  1. *There were no treatment-emergent serious adverse reactions observed in this trial.