Figure 1
From: Allergy Takes its Toll: The Role of Toll-like Receptors in Allergy Pathogenesis
Comparison of neonatal and adult responses to TLR activation: TNF- α and IL-10 responses were measured after stimulation with a TLR2 ligand (pansorbin) and TLR4 ligand (LPS). The cytokine levels in culture supernatants (picograms per milliliter) after 48 hours are displayed as median, and 5, 25, 75, and 95 percentile ranges and outlying values. All responses are shown as the levels in stimulated cultures after subtracting levels in the unstimulated control cultures. Data from adults (shaded bars) were compared with neonates (unshaded bars) using nonparametric Mann Whitney U test (with significance values as shown).