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Table 1 A Summary of the ASA Desensitization Regimens Used in Our 3 Patients

From: Description of 3 Cases in Vietnam of Aspirin Desensitization in Patients With Coronary Artery Disease and Coexisting Aspirin Hypersensitivity

Case

Clinical Manifestations of ASA Hypersensitivity

Premedication

Initial ASA Dose (mg)*

Final ASA Dose (mg)

Initial Dosing Interval (minutes)

Time to Achieve a Single Daily Dose of 100 mg of ASA (days)

Breakthrough Reactions (on Maintenance Dosage After Final Protocol Given)

Follow-up (months)

1

Angioedema/urticaria

Fexofenadine

0.0001

100

30

10

No

8

2

Urticaria

Fexofenadine

10

100

90

6

No

6

3

Urticaria

Fexofenadine

10

100

90

6

No

3

  1. *Initial dose of final protocol (milligram).