Table 2 Enzymatic Scavenger of Antioxidant Defense
Name of Scavenger | Acronym | Catalyzed Reaction |
|---|---|---|
Superoxide dismutase | SOD | M(n+1)+-SOD + O2- → Mn+-SOD + O2 Mn+-SOD + O2- + 2H+ → M(n+1)+-SOD + H2O2 |
Catalase | CAT | 2 H2O2 → O2 + 2 H2O H2O2 + Fe(III)-E → H2O + O = Fe(IV)-E(·+) H2O2 + O = Fe(IV)-E(·+)→ H2O + Fe(III)-E + O2 |
Glutathione peroxidase | GTPx | 2GSH +H2O2 → GSSG +2H2O 2GSH+ ROOH → GSSG + ROH + H2O |
Thioredoxin | TRX | Adenosine monophosphate + sulfite + thioredoxin disulfide = 5'-adenylyl sulfate + thioredoxin Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenyly+ sulfate + thioredoxin |
Peroxiredoxin | PRX | 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH |
Glutathione transferase | GST | RX + GSH = HX + R-S-GSH |