Gene | SNPs | rs Signatures | Haplotype Associated Phenotype | Race Background | PValue if Available | Reference |
---|---|---|---|---|---|---|
IL13 | - 1512A/C | rs1881457 | Severe RSV infection asthma | German children < 2 years old, | 0.009 (FASTEHPLUS) | ([100]) |
 | - 1112C/T | rs1800925 |  | hospitalized for RSV | 0.01183 (FAMHAP) |  |
 | Arg130Gln | rs20541 |  |  |  |  |
IL4 + IL13 | - 589C/T | rs2243250 | Severe RSV infection asthma | German children < 2 years old, | 0.0008 (FASTEHPLUS) | ([100]) |
 | - 1512A/C | rs1881457 |  | hospitalized for RSV | 0.0011 (FAMHAP) |  |
 | - 1112C/T | rs1800925 |  |  |  |  |
 | Arg130Gln | rs20541 |  |  |  |  |
IL4Rα + IL13 | Ile50Val Arg130Gln |  | Asthma + IgE levels | Chinese children 5 to 18 years of age | 0.013 (GMDR) | ([104]) |
IL4 + IL13 | - 589C/T | Â | Atopic dermatitis | Canadian children with family | 0.006 | ([95]) |
 | Arg130Gln |  | Atopy (Asthma not investigated) | history of asthma or atopy | 0.009 |  |