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Figure 1 | World Allergy Organization Journal

Figure 1

From: Differential Role of Hypoxia-Inducible Factor 1 Alpha in Toll-Like Receptor-Mediated and Allergic Inflammatory Reactions

Figure 1

Biochemical mechanisms of HIF-1 α protein accumulation and its differential functional role in IgE-mediated responses of basophils. Mechanisms leading to the accumulation and activation of HIF-1α protein during IgE-induced proallergic responses are presented. Differential functional roles of HIF-1 in cellular adaptation to inflammatory stress is summarized.

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