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Table 6 Change in Lung Function, eNO, and BHR Between 2 Visits According to Living Room Exposure to Dog Allergen*

From: Long-Term Effects of Allergen Sensitization and Exposure in Adult Asthma: A Prospective Study

Can f 1 (Living Room)

 

FEV1 (L)

FEV1 (% Predicted)

FVC (L)

FVC (% Predicted)

eNO (ppb)

PD20 (Doubling Doses)

Between Group Doubling Dose Difference PD20 (95% CI)

Not exposed

N

125

124

103

103

84

72

-1.00

 

Mean

0.01

2.43†

0.04

2.51

-3.39†

0.10

(-2.14 to 0.14)

 

(95% CI)

(-0.06 to 0.07)

(0.36-4.50)

(-0.07 to 0.14)

(-0.50 to 5.51)

(1.20-1.68)

(-0.39 to 0.58)

 

Exposed

N

39

39

34

34

35

14

t test, P = 0.085

 

Mean

-0.06

1.31

-0.01

1.81

-2.92†

1.10†

ANOVA, P = 0.019

 

(95% CI)

(-0.19 to 0.07)

(-3.93 to 6.55)

(-0.24 to 0.22)

(-5.44 to 9.06)

(1.03-1.85)

(0.33-1.86)

 
  1. *Lung function and BHR: mean changes (95% CI). eNO: geometric mean (95% CI for ratio).
  2. †P < 0.05 vs baseline.